I absolutely love this product.
"I absolutely love this product. I’m 70 years old and have been using it for a month. My skin looks smoother. My pores are tighter. It is definitely making a positive difference."
phyto nature e² regenerating daily exosome leave-on treatment
phyto nature e² regenerating daily exosome leave-on treatment
renew + resurface
Regular price
$229.00
Regular price
Sale price
$229.00
Unit price
per
- free shipping
- 2x loyalty points
- free gift on recurring orders
- cancel anytime
- free 30-day returns
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recommended for:
- mature or prematurely-aging skin
- fine lines and wrinkles
- loss of firmness and elasticity
Daily exosome leave-on visibly smooths and supports skin regeneration. Formulated with next-gen exosomes and enzymes, this lightweight, silky leave-on helps reawaken skin’s natural surface renewal process, improving natural regeneration by 86%.*
Exfoliating enzymes help clear away dull surface cells, revealing smoother, brighter skin. A regenerative exosome blend acts in multiple layers of skin’s surface, visibly diminishing fine lines and wrinkles. In an independent clinical study, fine lines and wrinkles were visibly diminished in 2 weeks.*
*Versus untreated skin. Based on in vitro testing.
**Results at 2 weeks, based on a reduction in visible signs of skin aging in an independent clinical study with 32 subjects, 2 applications/day.
description
description
recommended for:
- mature or prematurely-aging skin
- fine lines and wrinkles
- loss of firmness and elasticity
Daily exosome leave-on visibly smooths and supports skin regeneration. Formulated with next-gen exosomes and enzymes, this lightweight, silky leave-on helps reawaken skin’s natural surface renewal process, improving natural regeneration by 86%.*
Exfoliating enzymes help clear away dull surface cells, revealing smoother, brighter skin. A regenerative exosome blend acts in multiple layers of skin’s surface, visibly diminishing fine lines and wrinkles. In an independent clinical study, fine lines and wrinkles were visibly diminished in 2 weeks.*
*Versus untreated skin. Based on in vitro testing.
**Results at 2 weeks, based on a reduction in visible signs of skin aging in an independent clinical study with 32 subjects, 2 applications/day.
benefits
benefits
- Regenerative exosome blend helps diminish the appearance of fine lines + wrinkles
- Accelerates skin's natural cellular renewal
- Resurfaces to reveal brighter, smoother skin every day
how to use
how to use
Apply to clean skin. Allow to absorb, then follow with the rest of your skin care routine. Use twice daily.
key ingredients
key ingredients
Pumpkin enzyme: Exfoliates to reveal brighter, smoother skin daily
Regenerative exosome blend: Acts in multiple layers of skin’s surface, visibly diminishing fine lines and wrinkles
Botanical blend with phyto glycogen + prickly pear: Visibly brightens and smooths
Bio-fermented acetyl glucosamine: Hydrates and provides antioxidant protection
ingredients
ingredients
Water/Aqua/Eau, Lactobacillus/Pumpkin Ferment Extract, Propanediol, Lactococcus Ferment Lysate, Ethoxydiglycol, Hydrolyzed Soy Protein, Acetyl Glucosamine, Hydroxyacetophenone, Lactic Acid, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Salvia Sclarea (Clary) Oil, Pyrus Malus (Apple) Fruit Extract, Viola Odorata Leaf Extract, Acacia Senegal Gum Extract, Curcuma Longa (Turmeric) Root Extract, Mucor Miehei Extract, Lavandula Spica (Lavender) Flower/Leaf/Stem Extract, Rosmarinus Officinalis (Rosemary) Leaf Oil, Litsea Cubeba Fruit Oil, Camellia Japonica Flower Extract, Glycerin, Mentha Piperita (Peppermint) Oil, Butylene Glycol, Lactobacillus Ferment, Glycogen, Urea, Caprylyl Glycol, Phospholipids, Glucosamine HCl, Xanthan Gum, PEG-40 Hydrogenated Castor Oil, 1,2-Hexanediol, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Citric Acid, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Sodium Chloride, Sodium Citrate, Disodium EDTA, Sodium Benzoate, Potassium Sorbate, Limonene, Linalool, Citral.
Dermalogica is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are complete, up-to-date and/or error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.
professional skin treatment pairing
pro firm skin treatment
60 minutes
firm + retexturizing treatment
exo booster
booster
clinically proven to enhance post procedure results
Overall rating: 4.8003597 / 5 from 556 reviews.
AI Generated Review Summary
Phyto Nature e² is a leave-on product recommended for mature or prematurely-aging skin, known for visibly smoothing and supporting skin regeneration. It is formulated with next-gen exosomes and enzymes, offering lightweight and silky texture that absorbs quickly without residue. Many customers report smoother, firmer, and more radiant skin, with noticeable results in fine lines and wrinkles within two weeks.
Summary topics
- Absorption Speed: 26%
- Skin Feel: 38%
- Skin Appearance: 27%
- Texture: 25%
- Hydration: 20%
Review topics: ["absorbs","redness","improvement","difference","feels","skin","looks","buy","reduction","texture","results","treatment","smell","glow","wrinkles","exfoliant","formula","face","irritation","lines","bottle","complexion","packaging","serum","ingredients","residue","consistency","works","appearance","fragrance"].
Review highlights
- "It feels lightweight, absorbs beautifully, and instantly makes my skin look fresher and more rejuvenated." —
- "The texture feels silky during application, absorbs quickly, and makes my skin look smoother and more refreshed." —
- "I really liked the pleasant scent and the light texture that absorbs quickly." —
Reviews
High hopes
"I’ve only been using the products for two weeks so I can’t really say that it’s a good thing. I’ve had to cut back to once a day as I have experienced stinging. That being said I have loved all Dermalogica for a long time and I have high hopes. At 74 years old my skin looks great and I give most of the credit to Dermalogica,"
As a 69 year old,
"As a 69 year old, and very concerned of looking fresh and hopefully a looking a little youthful for my age, ‘regenerating’ is essential for the price. Love the feel, the smell and the benefits!"
Less lines
"What a difference in my fine lines and dull skin after a week. Love this product."
Hardly see improvements on my
"Hardly see improvements on my skin. Expecting something more from a product on an expensive side. Disappointed."
Not What I Expected :/
"I have been using the Phyto Nature Regenerating Daily Formula as recommended (2x/day) for more than a month, and haven't seen any results."
Exosome
"I really like this product. It feels light and absorbs quickly. It is helping to soften my fine lines."
I use this every morning.
"I use this every morning. It makes my skin look amazing."
I have not seen the
"I have not seen the promised results Doubt I will purchase again"
Does Nothing
"I am seriously shocked at all the 5 star reviews for this product. I thought for the price it was going to give my skin some improvement but it truly did NOTHING. I am 31 and have some shallow forehead wrinkles that formed in the last year that I thought this would flatten nicely for how costly it is. It truly did nothing. I used morning and night as directed for 3 weeks and I have ZERO wrinkle improvement. It made my acne prone skin break out. The only reason it gets two stars is because my skin is sensitive and my skin did tolerate it well (did not burn or flake) besides for it causing acne. I'm really disappointed as I was counting on this to work! I am returning it."
Q&A
- Can I use this with the phyto firming serum?
- Hello Kris, Thank you for choosing Dermalogica. You can use the Phyto nature firming serum as your serum step after you apply the phyto E2 for your regeneration and/or exfoliation step. We offer free skin consultations via chat with our professional skin experts on https://www.dermalogica.com/pages/contact-us. We also offer free video consultations. Here is a link to book a free 20 minute video consultation with one of our professional skin therapists! https://www.dermalogica.com/pages/video-consultations-page We look forward to speaking to you. Kind Regards, Melissa Dermalogica Professional Skin Therapist
- is this product vegan friendly?
- Yes, we are certified vegan by PETA on all current Dermalogica product formulas.
- Does this have any fragrance in it??
- Hello Jennifer, Thank you for reaching out to Dermalogica. I'm happy to say that Dermalogica products are free from artificial/synthetic fragrances and colors. Any scent is naturally occurring due to the botanicals used. Kind Regards Willow Dermalogica Professional Skin Therapist
- Does it need to be stored in the refrigerator, since it contains exosomes?
- Hello Mark, Thank you for choosing Dermalogica. No, the Phyto Nature E2 does not need to be stored in the refrigerator at this time. The formula has been carefully developed and tested to remain stable at normal room temperature. As long as the product is stored according to the recommended guidelines—away from direct sunlight and excessive heat—its quality and effectiveness will be maintained. Kind Regards, Melissa Dermalogica Professional Skin Therapist
- Hello, can this be layered with the retinol cream at night?
- Hello Alex, Thank you for reaching out to Dermalogica. Yes, you may apply this along with your dynamic skin retinol seurm Kind Regards Willow Dermalogica Professional Skin Therapist
